MOSCOW, 30 Aug. Scientists of Tomsk Polytechnic University have developed the first domestic membranes for blood purification. They are designed for mobile filters and can be used in emergency situations. According to the researchers, the new membranes qualitatively remove leukocytes from donor blood components and work more efficiently than existing foreign analogues. The development was successfully tested at the Kirov Research Institute of Hematology and Blood Transfusion of the Federal Medical and Biological Agency of Russia, the TPU press service reported.
Leukofiltration is a mandatory procedure to improve the safety of transfused blood. The fact is that donor leukocytes can cause unwanted immune reactions in the patient. Therefore, at blood transfusion stations, donor blood undergoes a rather lengthy and expensive processing using special devices. //ria.ru/20230821/nauka-1890825163.html» data->
Scientists from the Research School of Chemical and Biomedical Technologies at Tomsk Polytechnic University (TPU) have developed import-substituting membranes for mobile filters. Passing blood through such mobile filters is an alternative way to purify it. It is especially relevant when it is necessary to perform an emergency blood transfusion in the field.
The membranes are the key element of the filter. They are special composites laid in layers with a microporous structure that provides blood filtration. Passing through the membranes, leukocytes are retained due to the size of the pores and the electrical charge on the surface of the fibers. -ratio=»0.5625″ data-crop-width=»600″ data-crop-height=»338″ data-source-sid=»not_rian_photo» class=»» />
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The technology for the production of new membranes is completely domestic. They are created from domestic polymers using domestic equipment — a unique multi-channel electrospinning system developed by scientists from Tomsk Polytechnic University with the support of the Priority-2030 federal program of the Ministry of Education and Science. The installation allows to produce complex filters with high quality characteristics.
“Membranes developed at the university are 40% more efficient than Japanese analogues, which are a recognized standard. That is, with a smaller thickness and fewer layers, they filter blood with the same efficiency as imported products. This property of membranes has a good effect on filter performance and speed of his work. The thinner the size of the filter element, the more blood it passes,» said Evgeniy Bolbasov, project manager, senior researcher at TPU Research School of Chemical and Biomedical Technologies.
As emphasized at the university, for the university, the successful implementation of the project to develop leukocyte filters is not only an opportunity to transform a rich theoretical basis into the field of practical solutions demanded by enterprises in the real sector of the economy.
» This is also a kind of growth point, thanks to which our students and graduate students are actively involved in research, learn to interact with industrial companies, quickly responding to their requests,” said Marina Trusova, Director of the Research School of Chemical and Biomedical Technologies at TPU.